MK-2048 is primarily utilized in the field of antiviral research, particularly in the development of treatments for HIV. It functions as an integrase inhibitor, targeting the integrase enzyme that is crucial for the replication of the HIV virus. By inhibiting this enzyme, MK-2048 effectively prevents the integration of viral DNA into the host genome, thereby halting the progression of the infection. This makes it a valuable compound in the study of new therapeutic strategies and in the design of more effective antiretroviral drugs. Its role in preclinical studies helps researchers understand the mechanisms of viral resistance and the potential for combination therapies to enhance treatment outcomes.