Doravirine is primarily used in the treatment of HIV-1 infection in adults. It is an antiretroviral medication that works by inhibiting the reverse transcriptase enzyme, which is essential for the replication of the HIV virus. This drug is often prescribed as part of a combination therapy, typically alongside other antiretroviral agents, to effectively manage and control the viral load in patients. It is particularly beneficial for those who have not previously received treatment for HIV or for individuals who need to switch therapies due to intolerance or resistance to other medications. Doravirine is valued for its efficacy and favorable safety profile, including a lower risk of neuropsychiatric side effects compared to some other antiretrovirals. It is administered orally, usually once daily, making it a convenient option for long-term HIV management.