Benznidazole is a nitroimidazole antiprotozoal agent with the chemical formula C₁₂H₁₂N₄O₅. It is primarily used in the treatment of Chagas disease, a parasitic infection caused by Trypanosoma cruzi. It is particularly effective in the acute phase of the disease, where it helps to reduce the parasite load and prevent the progression to chronic stages. The drug is also used in pediatric cases and can be administered to newborns if congenital transmission is suspected. In chronic cases, it may help in slowing the progression of cardiac and digestive complications associated with the disease. Additionally, benznidazole is sometimes used in preemptive treatment for individuals at high risk of infection, such as those receiving organ transplants from infected donors. Its application is crucial in endemic regions to control the spread of the disease and improve patient outcomes.