Liproxstatin-1 is primarily used in research focused on understanding and combating ferroptosis, a form of regulated cell death driven by iron-dependent lipid peroxidation. It serves as a potent inhibitor of ferroptosis, making it a valuable tool in studying cellular mechanisms and pathways associated with this process. Researchers utilize Liproxstatin-1 to explore its protective effects in various disease models, particularly those involving oxidative stress and neurodegeneration, such as Alzheimer's and Parkinson's diseases. Additionally, it is employed in studies related to ischemia-reperfusion injury, cancer, and other conditions where ferroptosis plays a critical role. Its application extends to drug development, where it helps in identifying potential therapeutic targets and evaluating the efficacy of new treatments aimed at mitigating ferroptosis-related damage.