Enterodiol is a mammalian lignan produced by the action of gut microbiota on dietary precursors found in plant-based foods, particularly flaxseeds and sesame seeds. It is recognized for its potential role in human health due to its antioxidant and weak estrogenic or anti-estrogenic properties. Because of this, enterodiol has been studied for its possible protective effects against hormone-related cancers, such as breast and prostate cancer. It may help modulate hormone metabolism and reduce the activity of enzymes involved in the activation of carcinogens. Additionally, enterodiol contributes to cardiovascular health by supporting lipid profile balance and reducing oxidative stress. Its presence in the body is often used as a biomarker of lignan intake and gut microbial activity, making it relevant in nutritional and epidemiological studies focused on diet and chronic disease prevention.