Cimicifugoside H2, a triterpene glycoside from Cimicifuga racemosa (black cohosh), is utilized in skincare formulations due to its anti-inflammatory and antioxidant properties, helping to reduce redness, soothe irritated skin, and calm sensitive or aging skin. In research settings, it is studied for neuroprotective applications and its ability to inhibit pro-inflammatory cytokines such as TNF-α and IL-6, positioning it as a potential lead compound for treating chronic inflammatory conditions like arthritis or neuroinflammatory disorders. Additionally, it is investigated for hormone-modulating effects, particularly in women's reproductive health to alleviate menopausal symptoms, though further studies are required to validate efficacy and safety.