Curlignan is a dibenzocyclooctadiene lignan isolated from the fruits of Schisandra chinensis (Chinese magnolia vine). It exhibits potent antioxidant and anti-inflammatory properties, helping to combat oxidative stress and inflammation. Research highlights its potential anti-cancer effects, particularly in modulating cell proliferation and apoptosis. Curlignan also shows hepatoprotective activity, supporting liver health, and has demonstrated inhibitory effects against HIV reverse transcriptase. As a specialty chemical derived from natural sources, it is used in pharmaceutical and nutraceutical research for hormone modulation, cardiovascular benefits, and overall cellular protection. Common sources include Schisandra fruits, with studies ongoing for its role in menopausal health and cancer prevention.