Agrimoniin is primarily known for its strong antioxidant and anti-inflammatory properties, making it valuable in natural medicine and dietary supplements. It has been studied for its potential to support gastrointestinal health, particularly in managing conditions like colitis and other inflammatory bowel diseases due to its ability to modulate immune responses and protect mucosal tissues.

It also exhibits antiviral activity, especially against certain enveloped viruses, by interfering with viral entry into host cells. This makes it a subject of interest in the development of plant-based antiviral agents.

In traditional herbal medicine, extracts rich in agrimoniin are used to treat diarrhea, sore throats, and minor wounds, thanks to its astringent and antimicrobial effects. Ongoing research explores its role in cancer prevention, where it may help induce apoptosis in abnormal cells and reduce oxidative stress linked to tumor development.

Due to its polyphenolic structure, agrimoniin contributes to the overall health benefits of herbal teas and nutraceuticals derived from plants like Agrimonia eupatoria (common agrimony), often used for detoxification and liver support.