Calcium (2E,4E)-hexa-2,4-dienoate is primarily used as a preservative in the food industry due to its antimicrobial properties. It effectively inhibits the growth of bacteria, yeast, and molds, extending the shelf life of various food products. Commonly found in baked goods, dairy products, and beverages, it helps maintain freshness and safety. Additionally, it is utilized in the pharmaceutical sector as an excipient in certain formulations to enhance stability. Its role in cosmetics includes acting as a preservative to prevent spoilage and ensure product integrity over time.