Trovafloxacin mesylate is primarily used as a broad-spectrum antibiotic in the treatment of various bacterial infections. It is effective against both Gram-positive and Gram-negative bacteria, making it suitable for respiratory tract infections, urinary tract infections, and skin infections. Additionally, it has been utilized in treating more severe conditions such as intra-abdominal infections and pneumonia. Its ability to penetrate tissues effectively allows it to target infections in hard-to-reach areas. However, its use has been restricted in some regions due to potential side effects, particularly liver toxicity. It is often reserved for cases where other antibiotics have proven ineffective.