Dehydrobruceine A is a quassinoid compound used primarily in biochemical research for its potential antimalarial properties, demonstrating activity against Plasmodium falciparum, the parasite responsible for malaria. It is also investigated for anti-inflammatory effects and anticancer potential, particularly in inhibiting the growth of tumor cells such as colon and liver cancer cells in vitro. Derived from traditional medicinal plants like Brucea javanica, its bitter taste has sparked interest in its role in herbal remedies for digestive stimulation. As a niche research intermediate, it shows promise as a lead compound for developing treatments for chronic inflammatory diseases and cancer, though it lacks widespread clinical approval.