Used primarily in the synthesis of artemisinin, a key antimalarial drug. It serves as a crucial intermediate in the semi-synthetic production of artemisinin derivatives, which are essential components of artemisinin-based combination therapies (ACTs). These therapies are the first-line treatment for uncomplicated Plasmodium falciparum malaria recommended by the World Health Organization. Due to its role in enabling large-scale, cost-effective production of artemisinin, dihydroartemisinic acid supports global efforts to combat malaria, especially in resource-limited regions. Its availability through biosynthetic or semi-synthetic routes helps stabilize supply and reduce dependence on plant extraction from Artemisia annua.