8-Aminoquinoline-3-carboxylic acid
≥95%
Reagent
Code: #137098
CAS Number
1416439-58-1
blur_circular Chemical Specifications
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Molecular Information
Weight
188.18 g/mol
Formula
C₁₀H₈N₂O₂
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Registry Numbers
MDL Number
MFCD22690569
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Storage & Handling
Storage
Room temperature, away from light, stored in inert gas
description Product Description
Used primarily in the synthesis of antimalarial drugs, particularly as a key intermediate in the production of 8-aminoquinoline derivatives like primaquine and tafenoquine. These compounds are critical for treating liver-stage malaria parasites, including dormant forms of Plasmodium vivax and Plasmodium ovale, helping prevent relapses. Also investigated for its potential in developing new antimicrobial and antiparasitic agents due to its ability to intercalate into biological structures and modulate enzyme activity. Its carboxylic acid functionality allows for easy derivatization, making it valuable in medicinal chemistry for creating compound libraries aimed at targeting infectious diseases.
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