Clemizole is primarily known for its antihistaminic properties and has been used in the treatment of allergic conditions such as hay fever, urticaria, and other allergic skin reactions. It acts by blocking histamine H1 receptors, thereby reducing symptoms like itching, sneezing, and runny nose. In recent years, clemizole has gained attention for its potential antiviral activity, particularly against hepatitis C virus (HCV). It has been shown to inhibit the viral RNA-dependent RNA polymerase (NS5B), making it a candidate for repurposing in antiviral therapies. Research has also explored its use in combination with other antiviral agents to enhance efficacy. Additionally, studies suggest clemizole may have activity against certain parasitic infections and has been investigated for its effects on ion channels, which could open avenues for neurological or cardiac applications. However, these uses remain largely experimental.