3-(6-Chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol hydrochloride

95%

Reagent Code: #74414
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CAS Number 188416-20-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 420.22 g/mol
Formula C₁₆H₁₄Cl₂F₃N₅O
thermostat Physical Properties
Melting Point 126-130°C
inventory_2 Storage & Handling
Storage room temperature, dry

description Product Description

This compound serves as a key intermediate in the synthesis of voriconazole, a triazole antifungal agent used in medicinal chemistry. Voriconazole targets fungal enzymes involved in ergosterol biosynthesis, essential for fungal cell membrane integrity, thereby inhibiting fungal growth and treating infections such as candidiasis and aspergillosis. The hydrochloride salt form of this intermediate enhances solubility, facilitating its use in pharmaceutical synthesis. Ongoing research explores applications against drug-resistant fungal strains through derivatives like voriconazole.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 50mg
10-20 days ฿2,410.00
inventory 250mg
10-20 days ฿7,260.00

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