3-(6-Chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol hydrochloride
95%
science Other reagents with same CAS 188416-20-8
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description Product Description
This compound serves as a key intermediate in the synthesis of voriconazole, a triazole antifungal agent used in medicinal chemistry. Voriconazole targets fungal enzymes involved in ergosterol biosynthesis, essential for fungal cell membrane integrity, thereby inhibiting fungal growth and treating infections such as candidiasis and aspergillosis. The hydrochloride salt form of this intermediate enhances solubility, facilitating its use in pharmaceutical synthesis. Ongoing research explores applications against drug-resistant fungal strains through derivatives like voriconazole.
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