Miconazole nitrate is widely used as an antifungal medication to treat various fungal infections. It is commonly applied topically to the skin to address conditions such as athlete's foot, ringworm, and jock itch. The compound works by disrupting the fungal cell membrane, effectively inhibiting the growth of fungi.

In addition to skin infections, it is also used in the treatment of vaginal yeast infections, often available in the form of creams, powders, or suppositories. For oral thrush, a fungal infection in the mouth, miconazole nitrate is available as an oral gel, providing targeted relief by directly applying the medication to the affected area.

Its broad-spectrum antifungal properties make it effective against a variety of fungal species, including Candida and dermatophytes. Due to its efficacy and relatively low risk of systemic absorption when used topically, it is a preferred choice for treating localized fungal infections.