AN2718 is a novel antifungal compound primarily developed for the treatment of onychomycosis (nail fungus) and other dermatophyte infections of the skin. It demonstrates broad-spectrum activity against dermatophytes, yeasts including Candida species, and other pathogenic fungi. The compound functions by selectively inhibiting dihydroorotate dehydrogenase (DHODH), an enzyme critical for pyrimidine biosynthesis in fungi, thereby disrupting DNA and RNA synthesis essential for fungal proliferation. This targeted mechanism enhances its effectiveness against drug-resistant strains. AN2718 is formulated for topical application, such as in solutions or nail lacquers, to achieve deep penetration into nails and skin. Research continues to evaluate its clinical efficacy, safety, and potential for treating conditions like athlete's foot, ringworm, and oral thrush.