(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramide
99%
Reagent
Code: #51743
CAS Number
368421-58-3
blur_circular Chemical Specifications
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Molecular Information
Weight
312.33 g/mol
Formula
C₁₃H₁₄F₂N₄OS
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Storage & Handling
Storage
room temperature, dry
description Product Description
This chiral compound serves as a key intermediate in the development and synthesis of triazole-based antifungal agents, owing to its structural features resembling those drugs. The derived antifungals inhibit ergosterol synthesis, a vital component of fungal cell membranes, disrupting integrity and function, particularly against Candida and Aspergillus species causing systemic infections. It supports research for pharmaceutical treatments and potential agricultural fungicides. The specific (2R,3R) stereochemistry enhances binding affinity to target enzymes in the final agents, boosting efficacy and minimizing resistance.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White to Off-White Solid |
| Purity (%) | 98.5-100 |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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