(S)-3-(tert-Butyl(2-(2,4-difluorophenyl)-2-hydroxyethyl)amino)propanenitrile

97%

Reagent Code: #38407
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CAS Number 782482-51-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 282.33 g/mol
Formula C₁₅H₂₀F₂N₂O
badge Registry Numbers
MDL Number MFCD18632987
inventory_2 Storage & Handling
Storage Room temperature, dry and sealed

description Product Description

This compound is a key chiral intermediate in the synthesis of triazole antifungal pharmaceuticals, such as posaconazole. Its structure, featuring a 2,4-difluorophenyl moiety, tertiary alcohol, tert-butylamino group, and propanenitrile chain, is incorporated into the active drugs that target fungal cytochrome P450 enzymes (e.g., 14α-demethylase), inhibiting ergosterol biosynthesis and fungal growth in pathogens like Candida and Aspergillus species. The nitrile group enables further synthetic modifications to optimize efficacy and safety profiles.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿1,143.00
inventory 250mg
10-20 days ฿2,295.00

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