(R)-2-((2-(Hydroxydiphenylmethyl)Pyrrolidin-1-Yl)Methyl)-6-(Trifluoromethyl)Phenol
95%
Reagent
Code: #231658
CAS Number
1392130-33-4
blur_circular Chemical Specifications
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Molecular Information
Weight
427.46 g/mol
Formula
C₂₅H₂₄F₃NO₂
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Storage & Handling
Storage
Room temperature
description Product Description
Used primarily in the synthesis of antifungal medications, particularly as an intermediate in the production of structurally complex agents targeting Candida and Aspergillus species. Its chiral structure enhances binding selectivity to fungal cell membrane components, improving efficacy and reducing off-target effects. Also employed in research settings to develop novel derivatives with improved pharmacokinetic profiles, including better metabolic stability and tissue penetration. The presence of trifluoromethyl and hydroxydiphenyl groups contributes to lipophilicity, aiding in membrane interaction and antifungal activity.
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