(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol

97%

Reagent Code: #113140
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CAS Number 133775-25-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 269.25 g/mol
Formula C₁₂H₁₃F₂N₃O₂
thermostat Physical Properties
Boiling Point 485.0±55.0°C at 760 mmHg
inventory_2 Storage & Handling
Storage 2-8°C, store under inert gas

description Product Description

This compound serves as a key intermediate in the pharmaceutical industry for the synthesis of triazole antifungal agents. It possesses a 1,2,4-triazole ring and a 2,4-difluorophenyl substituent, structural features typical of azole antifungals that target ergosterol biosynthesis in fungal cells, disrupting membrane integrity. The (2R,3R) configuration is crucial for the stereoselectivity in downstream reactions leading to active pharmaceuticals effective against a broad spectrum of fungi, including Candida and Aspergillus species. It is employed in the development of formulations such as oral, topical, and intravenous drugs for treating systemic and localized fungal infections.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿315.00
inventory 5g
10-20 days ฿3,582.00
inventory 250mg
10-20 days ฿468.00
inventory 1g
10-20 days ฿1,170.00

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