Dolasetron is primarily used in the prevention and treatment of nausea and vomiting caused by chemotherapy, radiation therapy, or surgery. It is particularly effective in managing acute and delayed phases of chemotherapy-induced nausea and vomiting, making it a valuable option for patients undergoing cancer treatment. Additionally, it is administered postoperatively to help patients recover comfortably by reducing the risk of nausea and vomiting after anesthesia. Dolasetron works by blocking 5-HT3 serotonin receptors in the brain and gastrointestinal tract, which are involved in triggering the vomiting reflex. Its efficacy and tolerability make it a commonly prescribed antiemetic in clinical settings. It is available in injection or tablet forms and should be used under medical supervision for optimal safety and effectiveness.