Gliquidone is a sulfonylurea derivative used as an active pharmaceutical ingredient (API) in the formulation of oral hypoglycemic agents for the management of type 2 diabetes mellitus. Chemically, it is 1-[4-(2-butyl-4,6-dioxo-1H-pyrimidin-5-yl)sulfonyl]phenyl]-3-cyclohexylurea, with a molecular formula of C27H33N3O6S and molecular weight of 527.64 g/mol.

It acts by stimulating insulin secretion from pancreatic beta cells in response to glucose, thereby lowering blood glucose levels. Gliquidone is particularly suitable for patients with renal impairment due to its hepatic metabolism and biliary excretion, minimizing renal toxicity risks.

As a chemical reagent, gliquidone is supplied as a white to off-white powder with high purity (>97.5%), confirmed by infrared spectroscopy, melting point (177-188°C), and chromatographic analysis. It is utilized in pharmaceutical research, drug development, and manufacturing processes for antidiabetic medications.

Handling requires standard laboratory precautions; it should be stored in a cool, dry place away from light and moisture to maintain stability.