Tert-butyl(S)-2-cyano-4,4-difluoropyrrolidine-1-carboxylate
98%
science Other reagents with same CAS 483366-14-9
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description Product Description
Used in pharmaceutical synthesis as a chiral building block for developing protease inhibitors, particularly in the manufacture of antidiabetic drugs like DPP-4 inhibitors. Its fluorinated pyrrolidine structure enhances metabolic stability and binding selectivity. The tert-butoxycarbonyl (Boc) group protects the nitrogen during peptide coupling reactions, while the nitrile functionality allows further transformation into amides or tetrazoles. Commonly employed in asymmetric synthesis to introduce stereochemical control in active pharmaceutical ingredients (APIs).
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