Tert-butyl(2s,4r)-2-cyano-4-fluoropyrrolidine-1-carboxylate
97%
Reagent
Code: #244311
CAS Number
1330286-47-9
blur_circular Chemical Specifications
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Molecular Information
Weight
214.24 g/mol
Formula
C₁₀H₁₅FN₂O₂
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of antiviral and antidiabetic drugs. Its chiral structure makes it valuable for constructing stereoselective molecules, ensuring high enantiomeric purity in active pharmaceutical ingredients. Commonly employed in the preparation of protease inhibitors and DPP-4 inhibitors, where the tert-butyl carbamate group acts as a protecting group during peptide coupling and cyclization reactions. Its fluorinated pyrrolidine core enhances metabolic stability and bioavailability in final drug compounds.
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