3-(Trifluoromethyl)cinnamic acid, predominantly trans
98%
Reagent
Code: #239622
Alias
3-(trifluoromethyl)cinnamic acid
CAS Number
779-89-5
blur_circular Chemical Specifications
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Molecular Information
Weight
216.16 g/mol
Formula
CF₃C₆H₄CH=CHCO₂H
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Registry Numbers
EC Number
212-301-6
MDL Number
MFCD00004393
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Physical Properties
Melting Point
135-137 °C(lit.)
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Storage & Handling
Storage
Room temperature
description Product Description
Used in pharmaceutical synthesis as an intermediate for bioactive compounds, particularly in the development of antidiabetic and anti-inflammatory agents. Its trifluoromethyl group enhances metabolic stability and lipophilicity, making it valuable in medicinal chemistry for optimizing drug candidates. Also employed in the preparation of liquid crystals and organic semiconductors due to its rigid structure and electron-withdrawing properties. Commonly utilized in conjugation reactions, such as click chemistry and peptide coupling, for building complex molecular architectures.
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