Saxagliptin hydrate
10mM in DMSO
Reagent
Code: #233824
CAS Number
945667-22-1
blur_circular Chemical Specifications
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Molecular Information
Weight
333.43 g/mol
Formula
C₁₈H₂₅N₃O₂·H₂O
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Registry Numbers
EC Number
641-082-3
MDL Number
MFCD26131254
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Physical Properties
Melting Point
138 °C
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Storage & Handling
Storage
-20°C
description Product Description
Used in the management of type 2 diabetes mellitus as an oral antihyperglycemic agent. It functions by inhibiting the dipeptidyl peptidase-4 (DPP-4) enzyme, which increases the levels of active incretin hormones such as GLP-1 and GIP. This enhances glucose-dependent insulin release from pancreatic beta cells and reduces glucagon secretion, leading to lower fasting and postprandial blood glucose levels. Typically prescribed as monotherapy or in combination with other antidiabetic agents like metformin, sulfonylureas, or insulin. Its use improves glycemic control without significant risk of hypoglycemia or weight gain, making it suitable for long-term diabetes management.
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