Used primarily in the treatment of type 2 diabetes mellitus, this compound functions as an insulin sensitizer by activating peroxisome proliferator-activated receptor gamma (PPAR-γ). It helps improve glycemic control by increasing insulin sensitivity in adipose tissue, muscle, and liver, thereby reducing insulin resistance—a key defect in type 2 diabetes. It is typically prescribed as an adjunct to diet and exercise and may be used alone or in combination with other antidiabetic agents such as metformin or insulin. Its use has declined in some regions due to concerns over cardiovascular risks, but it remains an option in specific patient populations under careful monitoring.