Used primarily in the treatment of diabetic complications, particularly diabetic retinopathy and diabetic nephropathy. It works by inhibiting protein kinase C-beta (PKC-β), an enzyme involved in vascular and inflammatory pathways that contribute to microvascular damage in diabetes. By targeting this pathway, it helps reduce retinal vascular leakage, slow vision loss, and improve kidney function in diabetic patients. It has been investigated as an oral therapy to delay progression of eye and kidney damage, offering a potential option for long-term management of diabetes-related microvascular issues.