(R)-Ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-difluoro-3-hydroxypropanoate

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Reagent Code: #229523
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CAS Number 95058-92-7

science Other reagents with same CAS 95058-92-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 254.23 g/mol
Formula C₁₀H₁₆F₂O₅
badge Registry Numbers
MDL Number MFCD09833384
inventory_2 Storage & Handling
Storage 2-8°C, sealed, dry

description Product Description

Used as a key chiral intermediate in the synthesis of antidiabetic drugs, particularly in the production of DPP-4 inhibitors like sitagliptin. Its stereochemistry allows for high selectivity and efficacy in the final active pharmaceutical ingredient. The compound’s fluorinated structure enhances metabolic stability and bioavailability in the resulting drug. Commonly employed in asymmetric synthesis routes due to its well-defined stereocenters and compatibility with enzymatic or catalytic transformations.

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inventory 1g
10-20 days ฿1,730.00

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(R)-Ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-difluoro-3-hydroxypropanoate
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Used as a key chiral intermediate in the synthesis of antidiabetic drugs, particularly in the production of DPP-4 inhibitors like sitagliptin. Its stereochemistry allows for high selectivity and efficacy in the final active pharmaceutical ingredient. The compound’s fluorinated structure enhances metabolic stability and bioavailability in the resulting drug. Commonly employed in asymmetric synthesis routes due to its well-defined stereocenters and compatibility with enzymatic or catalytic transformations.

Used as a key chiral intermediate in the synthesis of antidiabetic drugs, particularly in the production of DPP-4 inhibitors like sitagliptin. Its stereochemistry allows for high selectivity and efficacy in the final active pharmaceutical ingredient. The compound’s fluorinated structure enhances metabolic stability and bioavailability in the resulting drug. Commonly employed in asymmetric synthesis routes due to its well-defined stereocenters and compatibility with enzymatic or catalytic transformations.

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