Used as a key chiral intermediate in the synthesis of pharmaceuticals, particularly in the development of antiviral and antidiabetic drugs. Its fluorinated pyrrolidine structure enhances metabolic stability and bioavailability in drug candidates. Commonly employed in the preparation of protease inhibitors and DPP-4 inhibitors for type 2 diabetes treatment. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies due to its rigid backbone and hydrogen-bonding capability.