PF-04995274

10mM in DMSO

Reagent Code: #224079
fingerprint
CAS Number 1331782-27-4

science Other reagents with same CAS 1331782-27-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 432.22 g/mol
Formula C₂₃H₃₂N₂O₆
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in research for the treatment of type 2 diabetes, this compound acts as a selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). By inhibiting this enzyme, it helps reduce cortisol levels in key tissues such as the liver and adipose tissue, which may improve insulin sensitivity and glucose metabolism. It has been investigated for its potential to lower blood glucose without directly stimulating insulin secretion, making it a candidate for addressing metabolic dysfunction. Studies have focused on its oral bioavailability and tissue-specific activity, supporting its development as part of novel antidiabetic therapies.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿5,680.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB
PF-04995274
No image available
Used in research for the treatment of type 2 diabetes, this compound acts as a selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). By inhibiting this enzyme, it helps reduce cortisol levels in key tissues such as the liver and adipose tissue, which may improve insulin sensitivity and glucose metabolism. It has been investigated for its potential to lower blood glucose without directly stimulating insulin secretion, making it a candidate for addressing metabolic dysfunction. Studies have focused on its oral bioavailability and tissue-specific activity, supporting its development as part of novel antidiabetic therapies.
Mechanism -
Appearance -
Longevity -
Strength -
Storage -
Shelf Life -
Allergen(s) -
Dosage (Range) -
Dosage (Per Day) -
Mix Method -
Heat Resistance -
Stable in pH range -
Solubility -
Product Types -
INCI -

Purchase History for

Loading purchase history...