Omarigliptin (MK-3102)
10mM in DMSO
Reagent
Code: #221270
CAS Number
1226781-44-7
science Other reagents with same CAS 1226781-44-7
blur_circular Chemical Specifications
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Molecular Information
Weight
398.43 g/mol
Formula
C₁₇H₂₀F₂N₄O₃S
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Registry Numbers
MDL Number
MFCD22573261
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Storage & Handling
Storage
-20°C
description Product Description
Used in the management of type 2 diabetes mellitus as a once-weekly oral antihyperglycemic agent. It functions by inhibiting the dipeptidyl peptidase-4 (DPP-4) enzyme, thereby increasing the levels of active incretin hormones such as GLP-1 and GIP. This leads to enhanced glucose-dependent insulin secretion from pancreatic beta cells and reduced glucagon secretion from alpha cells, resulting in lower fasting and postprandial blood glucose levels. Its weekly dosing regimen improves patient adherence compared to daily DPP-4 inhibitors. It is typically used as an adjunct to diet and exercise and may be combined with other antidiabetic agents such as metformin or insulin.
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