N-Carbamimidoyl-N-methylglycine hemi-2-hydroxysuccinic acid salt, commonly known as creatine malate, is a specialized salt form of creatine used primarily in dietary supplements to support athletic performance, muscle growth, and energy metabolism. It offers improved solubility and bioavailability compared to standard creatine monohydrate. In pharmaceutical and biochemical research, it is investigated for potential therapeutic applications in antidiabetic treatments, neurodegenerative disorders (e.g., Parkinson's disease), and conditions involving impaired cellular energy production. The malate component aids in formulation stability and pH buffering. Also utilized as a building block in synthetic biology and peptide-related studies.