Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of antidiabetic agents. Its rigid bicyclic structure and functional groups make it valuable for modifying drug potency and metabolic stability. Commonly employed in the preparation of glucokinase activators, which are investigated for the treatment of type 2 diabetes. Also utilized in medicinal chemistry to construct structurally constrained analogs of bioactive molecules, enhancing selectivity and improving pharmacokinetic properties.