6-Fluoro-2-(2'-fluoro-[1,1'-biphenyl]-4-yl)-3-methylquinoline-4-carboxylic acid
10mM in DMSO
Reagent
Code: #186876
CAS Number
96187-53-0
blur_circular Chemical Specifications
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Molecular Information
Weight
375.37 g/mol
Formula
C₂₃H₁₅F₂NO₂
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Storage & Handling
Storage
-20°C
description Product Description
Used as a key intermediate in the synthesis of trelagliptin, an antidiabetic drug belonging to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors. It plays a critical role in enhancing the stability and pharmacokinetic profile of the final active pharmaceutical ingredient. Its fluorinated aromatic structure contributes to improved metabolic resistance and target binding affinity, making it valuable in the development of once-weekly oral medications for type 2 diabetes. The compound is primarily utilized in controlled laboratory and industrial settings during the late-stage assembly of the drug substance.
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