Pramlintide acetate is primarily used in the management of diabetes, specifically type 1 and type 2 diabetes. It is administered as an adjunct to mealtime insulin therapy to improve glycemic control. The drug works by slowing gastric emptying, suppressing glucagon secretion, and promoting satiety, which helps in reducing postprandial blood glucose spikes. This makes it particularly beneficial for patients who struggle to achieve target blood glucose levels despite optimized insulin therapy. Additionally, pramlintide acetate can aid in weight management, as it often leads to a reduction in caloric intake due to its appetite-suppressing effects. It is typically injected subcutaneously before major meals, and its use requires careful monitoring to avoid hypoglycemia, especially when combined with insulin. Overall, it serves as a valuable tool in comprehensive diabetes care, helping patients achieve better glucose control and improved quality of life.