NNC45-0781 is primarily used in research settings to study its effects on specific biological pathways, particularly those related to metabolic regulation and insulin sensitivity. It has been investigated for its potential role in managing conditions like type 2 diabetes by targeting receptors involved in glucose metabolism. Additionally, it serves as a tool in pharmacological studies to understand the mechanisms of action of similar compounds, aiding in the development of new therapeutic agents. Its application is largely confined to preclinical studies, where it helps in evaluating efficacy, safety, and pharmacokinetics.