Reboxetine is primarily used as an antidepressant, specifically a selective norepinephrine reuptake inhibitor (NRI). It is prescribed to treat major depressive disorder by increasing the levels of norepinephrine in the brain, which helps improve mood and reduce symptoms of depression. Additionally, it is sometimes used off-label to manage attention deficit hyperactivity disorder (ADHD) and certain anxiety disorders. Its mechanism of action focuses on enhancing concentration and energy levels, making it beneficial for patients experiencing fatigue or lack of focus. However, it is not typically the first-line treatment due to its side effect profile, which includes insomnia, dry mouth, and increased sweating. It is often considered when other antidepressants have not been effective.