Epothilone D is primarily utilized in cancer research and treatment due to its ability to stabilize microtubules, similar to the mechanism of taxanes. It is investigated as a potential chemotherapeutic agent, particularly for cancers that have developed resistance to other treatments like paclitaxel. Its application extends to preclinical studies where it is used to understand tumor biology and evaluate its efficacy in inhibiting cancer cell proliferation. Additionally, Epothilone D is explored in combination therapies to enhance its anticancer effects and reduce side effects. Its role in targeting drug-resistant cancers makes it a valuable compound in oncology research.