Used in research for its potential antitumor, cytotoxic, anti-inflammatory, and antimicrobial properties, particularly in studies involving cancer cell lines where it induces apoptosis and inhibits cell proliferation. Also examined for anti-inflammatory effects at the cellular level and antimicrobial activity against pathogens. Investigated as a natural product lead for developing new chemotherapeutic agents, treatments for infections, and therapies for chronic inflammatory diseases. Isolated from certain Euphorbia species, it contributes to the plant's defense mechanisms and serves as a reference standard for analyzing similar diterpene lactones in natural products. Studied for its ecological, pharmacological, and biochemical significance.