Deoxyshikonin is widely used for its potent biological activities, particularly in traditional medicine and modern pharmaceutical research. It exhibits strong anti-inflammatory and antimicrobial properties, making it valuable in treating skin disorders such as wounds, burns, and ulcers. Its ability to promote tissue regeneration and accelerate wound healing is well-documented.

In dermatology, deoxyshikonin is incorporated into topical formulations due to its effectiveness in managing acne and other inflammatory skin conditions. It also shows promising anticancer activity by inducing apoptosis in various cancer cell lines, including those of the liver, lung, and breast, through modulation of key signaling pathways.

Additionally, deoxyshikonin acts as an antioxidant, protecting cells from oxidative stress, which is beneficial in anti-aging skincare products. Its natural origin and low toxicity profile enhance its appeal in cosmetic and therapeutic applications. Ongoing research explores its potential in managing metabolic and neurodegenerative diseases due to its neuroprotective and anti-diabetic effects.