Manzamine A hydrochloride is primarily studied for its potential in cancer therapy due to its ability to inhibit the growth of various cancer cells. It has shown promising activity against certain types of tumors, particularly in preclinical studies. Additionally, it exhibits anti-inflammatory properties, making it a candidate for treating inflammatory diseases. Research also explores its potential as an antimalarial agent, as it has demonstrated effectiveness against Plasmodium species, the parasites responsible for malaria. Its unique structure and biological activities continue to drive interest in its therapeutic applications.