Midecamycin is primarily used as an antibiotic in the treatment of various bacterial infections. It is effective against respiratory tract infections, including bronchitis, pneumonia, and tonsillitis, caused by susceptible strains of bacteria. Additionally, it is utilized for skin and soft tissue infections, such as abscesses and cellulitis. Midecamycin is also prescribed for otitis media and sinusitis, providing relief from symptoms and combating the underlying bacterial cause. Its application extends to treating infections in the urogenital tract, including urethritis and cervicitis. Due to its broad-spectrum activity, it is particularly useful in cases where penicillin or other antibiotics are ineffective or contraindicated. It is often chosen for its relatively low incidence of side effects and its ability to be administered orally, making it convenient for outpatient treatment.