Apramycin sulfate salt is widely used in veterinary medicine as an effective antibiotic to treat bacterial infections in livestock, particularly in pigs, cattle, and poultry. It is effective against Gram-negative bacteria and is often administered to combat gastrointestinal and respiratory infections. Additionally, it is used in aquaculture to control bacterial diseases in fish and shellfish. Its low absorption rate in the gut makes it suitable for oral administration, ensuring targeted action in the digestive tract. Apramycin sulfate salt is also utilized in research settings to study antibiotic resistance mechanisms and develop new therapeutic strategies.