Tilmicosin is widely used in veterinary medicine, primarily for the treatment and prevention of respiratory diseases in livestock, such as cattle, sheep, and pigs. It is particularly effective against bacterial infections caused by pathogens like Pasteurella multocida, Mannheimia haemolytica, and Actinobacillus pleuropneumoniae. The antibiotic is administered through injection or as an additive in feed or water, ensuring rapid absorption and prolonged therapeutic effects. Its ability to concentrate in lung tissue makes it highly effective in targeting respiratory infections. Additionally, tilmicosin is used to control outbreaks of mycoplasmal infections in poultry, contributing to improved animal health and productivity. Its long-acting nature reduces the frequency of administration, making it a convenient choice for farmers and veterinarians.