Panipenem is primarily used as a broad-spectrum antibiotic in the treatment of severe bacterial infections. It is effective against a wide range of Gram-positive and Gram-negative bacteria, making it suitable for combating infections in various parts of the body, including respiratory tract infections, urinary tract infections, and intra-abdominal infections. Due to its potent antibacterial activity, it is often reserved for cases where other antibiotics have failed or when the infection is caused by multidrug-resistant pathogens. It is typically administered intravenously in hospital settings to ensure proper dosage and monitoring, especially in critically ill patients. Panipenem is often combined with betamipron to reduce nephrotoxicity, enhancing its safety profile during prolonged use. Its application is crucial in managing complex infections in immunocompromised patients or those with underlying health conditions.