Tazobactam sodium salt is primarily used as a β-lactamase inhibitor in combination with β-lactam antibiotics, such as piperacillin. It helps restore the effectiveness of antibiotics that would otherwise be degraded by bacterial enzymes, particularly in resistant strains. This combination is effective against a broad spectrum of Gram-positive and Gram-negative bacteria, including those producing extended-spectrum β-lactamases (ESBLs). It is commonly used in treating severe infections such as intra-abdominal infections, pneumonia, urinary tract infections, and sepsis, especially in hospital settings where antibiotic resistance is a concern.