(1R, 5S, 6S)-6-[1(R)-Hydroxyethyl]-1-methyl-2-[1-(2-thiazolin-2-yl)azetidin-3-ylsulfanyl]-1-carba-2-penem-3-carboxylic acid pivaloyloxymethyl ester
10mM in DMSO
Reagent
Code: #229631
CAS Number
161715-24-8
blur_circular Chemical Specifications
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Molecular Information
Weight
496.64 g/mol
Formula
C₂₃H₃₂N₂O₆S₂
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Registry Numbers
EC Number
1308068-626-2
MDL Number
MFCD17215369
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Physical Properties
Melting Point
140-142 °C
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Storage & Handling
Storage
-20°C
description Product Description
Used as a prodrug in antibacterial formulations, particularly effective against resistant Gram-positive and Gram-negative pathogens. The compound enhances oral bioavailability of the active β-lactam metabolite by improving intestinal absorption. Once absorbed, it is hydrolyzed to release the active carba-penem, which inhibits bacterial cell wall synthesis. Its structure provides stability against many β-lactamases, making it valuable in treating infections where standard antibiotics fail. Commonly indicated for respiratory, urinary tract, and skin infections caused by multidrug-resistant organisms.
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