Used primarily as a feed additive in veterinary medicine for ruminant animals like cattle and sheep, where it acts as an ionophore to modify rumen microbial balance, improving feed efficiency, digestion, and weight gain while reducing the risk of rumen acidosis. It also functions as an anticoccidial agent to control coccidiosis, a parasitic disease caused by protozoans in the intestinal tract, in both ruminants and poultry. Monensin B disrupts ion transport across cell membranes in protozoans and gram-positive bacteria. Commonly included in animal feed formulations for prevention of coccidial infections; not approved for use in lactating dairy animals due to potential residues or in humans due to toxicity concerns. Its ionophore properties make it useful in research for studying ion transport.